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[Analysis Case] Evaluation of Ingredients in Tablet-Type Headache Medicine

Comparison of ingredients between new products and those after harsh testing; estimation of the structure of unknown components.

We conducted LC/MS analysis to compare how the components in commercially available tablet-type headache medications change before and after harsh testing. The LC/MS total ion chromatogram (TIC) revealed the presence of characteristic components that were not found in the new product after the harsh testing, and the precise mass was identified through the MS spectrum. Furthermore, by performing LC/MS/MS analysis, we were able to estimate the structure based on the information from fragment ions. The combination of LC/MS and LC/MS/MS allows for the structural estimation of unknown components.

• Company：一般財団法人材料科学技術振興財団　MST
• Price：Other

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